Subthalamic and Thalamic Stereotactic Recordings and Stimulations in Patients with Intractable Epilepsy

Heinz Gregor Wieser, Dominik Zumsteg

192 pages, parution le 03/04/2008

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Résumé

This volume presents the experience of the Zurich Epilepsy Surgery Center with stereotactic recordings and stimulations of various subcortical nuclei, with special reference to the Forel H fields, the thalamic nuclei and the periaqueductal gray matter. Stereotactic lesions structures have frequently been performed with the aim to prevent seizure spread along preexisting and preferred seizure propagating pathways or to directly destroy diseased areas of the brain that act as a focus of epileptic discharges. Although the usefulness of stereotactic epilepsy surgery has been repeatedly challenged, the extensive knowledge deriving from early attempts to suppress seizures by stereotactic epilepsy surgery is relevant to the renewed interest in neurostimulation for the treatment of epilepsy. Deep Brain Stimulation (DBS) of these structures aims to influence these key "pacemaker" areas in the brain and is gaining increasing interest as a possible new surgical modality for treatment of patients with intractable epilepsy. Thus, the aim of this volume is to improve understanding of the involvement of subcortical structures in seizure genesis and propagation, and to address the important issues of DC recording/polarisation and biochemical measurement of excitatory and inhibitory transmitters released in the primary epileptogenic area during epileptic discharges.

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Preface
Abbreviations
Introduction
Anatomical and Physiological Basis for Stereotactic Exploration of Subcortical Structures in Patients with Epilepsy
Case Studies
Discussion
Conclusions and Outlook
References
Index
Appendix: Historical Note on Auguste Forel

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Caractéristiques techniques

	PAPIER	NUMERIQUE
Éditeur(s)	John Libbey
Auteur(s)	Heinz Gregor Wieser, Dominik Zumsteg
Parution	03/04/2008	03/04/2008
Nb. de pages	192	192
Format	21,5 x 30,5	-
Couverture	Relié	-
Poids	853g	-
Intérieur	2 couleurs	-
Contenu	-	PDF
EAN13	9782742006182	9782742009688
ISBN13	978-2-74-200618-2	-